Coeliac disease is an autoimmune condition where the ingestion of gluten triggers damage to the small intestine. Despite affecting around 1% of the population, many individuals remain undiagnosed for years—often due to varied and non-specific symptoms.
What’s the Challenge?
Subtle or Atypical Symptoms:
Not everyone presents with obvious digestive issues. Many experience fatigue, nutrient deficiencies, or neurological symptoms instead.
Delayed Diagnosis:
It can take years before coeliac disease is identified, increasing the risk of long-term complications.
Silent Coeliac Disease:
Some individuals have intestinal damage without noticeable symptoms, making screening even more important in at-risk groups.
Common Clinical Indicators
- Persistent fatigue
- Iron deficiency (with or without anaemia)
- Low vitamin B12 or folate
- Unexplained weight changes
- Fractures/reduced bone mineral density
- Recurrent mouth ulcers
- Skin conditions like dermatitis herpetiformis
- Brain fog
- Joint pain
Impact on Long-Term Health
If left untreated, coeliac disease may lead to:
- Osteoporosis
- Fertility issues
- Increased risk of other autoimmune conditions
- Ongoing nutrient deficiencies
- Reduced quality of life
Clinical Implications
- Early detection is key to preventing complications
- Screening involves blood tests followed by biopsy confirmation
- Testing must occur while consuming gluten
- First-degree relatives may benefit from screening due to genetic risk
What Does the Evidence Show?
- Many individuals remain undiagnosed despite regular healthcare contact
- Early adoption of a gluten-free diet significantly improves outcomes
- Ongoing follow-up is essential to monitor gut healing and nutritional status
Final Thoughts
If you’ve been experiencing ongoing symptoms or have unexplained nutrient deficiencies, it’s worth discussing coeliac screening with your healthcare provider.
Avoid removing gluten before testing, as this can interfere with diagnosis.
A clear diagnosis allows for targeted management, improved health outcomes, and long-term prevention of complications.



